Unravelling Checkpoint Inhibitor Associated Autoimmune Diabetes: From Bench to Bedside

Unravelling Checkpoint Inhibitor Associated Autoimmune Diabetes: From Bench to Bedside

Immune checkpoint inhibitors have transformed the landscape of oncological therapy, but at the price of a new array of immune related adverse events. Among these is β-cell failure, leading to checkpoint inhibitor-related autoimmune diabetes (CIADM) which entails substantial long-term morbidity. As o...

Full description

Bibliographic Details
Main Authors: Linda Wu, Venessa H. M. Tsang, Sarah C. Sasson, Alexander M. Menzies, Matteo S. Carlino, David A. Brown, Roderick Clifton-Bligh, Jenny E. Gunton
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Endocrinology
Subjects:
immune checkpoint inhibitor (ICI)
diabetes mellitus
type 1 diabetes
immune related adverse events
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.764138/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.764138/full

Similar Items