Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma

Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma

Background: It has been shown that a possible pathogenetic mechanism of neurodegeneration in the mouse model of glaucoma (DBA/2J) may be an alteration of kynurenic acid (KYNA) in the retina. This study aimed to verify the hypothesis that alterations of tryptophan (TRP) metabolism in DBA/2J mice is n...

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Bibliographic Details
Main Authors: Michal Fiedorowicz, Tomasz Choragiewicz, Waldemar A. Turski, Tomasz Kocki, Dominika Nowakowska, Kamila Wertejuk, Agnieszka Kamińska, Teresio Avitabile, Marlena Wełniak-Kaminska, Pawel Grieb, Sandrine Zweifel, Robert Rejdak, Mario Damiano Toro
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
glaucoma
kynurenine pathway
DBA/2J
retina
Online Access:https://www.mdpi.com/1422-0067/22/3/1039

Internet

https://www.mdpi.com/1422-0067/22/3/1039

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