Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity

Generation of a MyoD knock-in reporter mouse line to study muscle stem cell dynamics and heterogeneity

Summary: Myoblast determination protein 1 (MyoD) dynamics define the activation status of muscle stem cells (MuSCs), aiding in muscle tissue regeneration after injury. However, the lack of experimental platforms to monitor MyoD dynamics in vitro and in vivo has hampered the investigation of fate det...

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Bibliographic Details
Main Authors: Ryo Fujita, Seiya Mizuno, Taketaro Sadahiro, Takuto Hayashi, Takehito Sugasawa, Fumihiro Sugiyama, Yusuke Ono, Satoru Takahashi, Masaki Ieda
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Cell biology
Molecular biology
Stem cells research
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223006697

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223006697

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