Phosphorylation of AMPKα at Ser485/491 Is Dependent on Muscle Contraction and Not Muscle-Specific IGF-I Overexpression

Phosphorylation of AMPKα at Ser485/491 Is Dependent on Muscle Contraction and Not Muscle-Specific IGF-I Overexpression

Glucose is an important fuel for highly active skeletal muscles. Increased adenosine monophosphate (AMP)/adenosine triphosphate (ATP) ratios during repetitive contractions trigger AMP-activated protein kinase (AMPK), indicated by phosphorylation of AMPKα<sup>Thr172</sup>, which promotes...

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Bibliographic Details
Main Authors: Chih-Hsuan Chou, Elisabeth R. Barton
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
AMPK
skeletal muscle
IGF-I
muscle contraction
Online Access:https://www.mdpi.com/1422-0067/24/15/11950

Internet

https://www.mdpi.com/1422-0067/24/15/11950

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