Molecular cytogenetic characterization of canine histiocytic sarcoma: A spontaneous model for human histiocytic cancer identifies deletion of tumor suppressor genes and highlights influence of genetic background on tumor behavior

<p>Abstract</p> <p>Background</p> <p>Histiocytic malignancies in both humans and dogs are rare and poorly understood. While canine histiocytic sarcoma (HS) is uncommon in the general domestic dog population, there is a strikingly high incidence in a subset of breeds, su...

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Bibliographic Details
Main Authors: Abadie Jerome, Motsinger-Reif Alison, Thomas Rachael, Hedan Benoit, Andre Catherine, Cullen John, Breen Matthew
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/201