Clinical Outcomes of Third-Generation Cephalosporin Definitive Therapy for Bloodstream Infections Due to Enterobacterales with Potential AmpC Induction: A Single-Center Retrospective Study

Clinical Outcomes of Third-Generation Cephalosporin Definitive Therapy for Bloodstream Infections Due to Enterobacterales with Potential AmpC Induction: A Single-Center Retrospective Study

The recommended therapy for severe infections caused by AmpC-inducible Enterobacterales (AmpC-E) typically involves cefepime or carbapenems. In an era of emerging resistance to these antimicrobials, we aim to assess the impact of third-generation cephalosporins (3GCs) vs. alternative antibiotics on...

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Bibliographic Details
Main Authors: Gilles Vossius, Cécile Meex, Filip Moerman, Marie Thys, Marie Ernst, Marie-Eve Bourgeois, Léa Wagner, Thibaut Delahaye, Gilles Darcis
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pathogens
Subjects:
AmpC
Enterobacterales
Enterobacteriaceae
beta-lactamases
cephalosporins
antimicrobial resistance
Online Access:https://www.mdpi.com/2076-0817/12/9/1152

Internet

https://www.mdpi.com/2076-0817/12/9/1152

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