Nicotine acts on growth plate chondrocytes to delay skeletal growth through the alpha7 neuronal nicotinic acetylcholine receptor.
BACKGROUND: Cigarette smoking adversely affects endochondral ossification during the course of skeletal growth. Among a plethora of cigarette chemicals, nicotine is one of the primary candidate compounds responsible for the cause of smoking-induced delayed skeletal growth. However, the possible mech...
المؤلفون الرئيسيون: | , , , , , , |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
Public Library of Science (PLoS)
2008-01-01
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سلاسل: | PLoS ONE |
الوصول للمادة أونلاين: | http://europepmc.org/articles/PMC2596484?pdf=render |