Quantification of APOBEC3 Mutation Rates Affecting the <i>VP1</i> Gene of BK Polyomavirus In Vivo

Quantification of APOBEC3 Mutation Rates Affecting the <i>VP1</i> Gene of BK Polyomavirus In Vivo

Mutations in the BK polyomavirus (BKPyV) capsid accumulate in kidney transplant (KTx) recipients with persistent virus replication. They are associated with neutralization escape and appear to arise as a result of cytosine deamination by host cell APOBEC3A/B enzymes. To study the mutagenic processes...

Full description

Bibliographic Details
Main Authors: Dorian McIlroy, Cécile Peltier, My-Linh Nguyen, Louise Manceau, Lenha Mobuchon, Nicolas Le Baut, Ngoc-Khanh Nguyen, Minh-Chau Tran, The-Cuong Nguyen, Céline Bressollette-Bodin
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Viruses
Subjects:
APOBEC
innate immunity
polyomavirus
virus evolution
Online Access:https://www.mdpi.com/1999-4915/14/9/2077

Internet

https://www.mdpi.com/1999-4915/14/9/2077

Similar Items