miR-615 facilitates porcine epidemic diarrhea virus replication by targeting IRAK1 to inhibit type III interferon expression

miR-615 facilitates porcine epidemic diarrhea virus replication by targeting IRAK1 to inhibit type III interferon expression

Porcine epidemic diarrhea virus (PEDV) in the Coronavirus family is a highly contagious enteric pathogen in the swine industry, which has evolved mechanisms to evade host innate immune responses. The PEDV-mediated inhibition of interferons (IFNs) has been linked to the nuclear factor-kappa B (NF-κB)...

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Bibliographic Details
Main Authors: Hong-qing Zheng, Cheng Li, Xiao-fu Zhu, Wei-Xiao Wang, Bao-ying Yin, Wen-juan Zhang, Shu-lin Feng, Xun-hui Yin, He Huang, Yan-ming Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Microbiology
Subjects:
miR-615
IFN
innate immunity
porcine epidemic diarrhea virus
intestinal epithelial cells
miRNA high-throughput
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1071394/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.1071394/full

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