SMYD3 Promotes Cell Cycle Progression by Inducing Cyclin D3 Transcription and Stabilizing the Cyclin D1 Protein in Medulloblastoma

SMYD3 Promotes Cell Cycle Progression by Inducing Cyclin D3 Transcription and Stabilizing the Cyclin D1 Protein in Medulloblastoma

Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Maximum safe resection, postoperative craniospinal irradiation, and chemotherapy are the standard of care for MB patients. MB is classified into four subgroups: Shh, Wnt, Group 3, and Group 4. Of these subgroups, patients with...

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Bibliographic Details
Main Authors: Swapna Asuthkar, Sujatha Venkataraman, Janardhan Avilala, Katherine Shishido, Rajeev Vibhakar, Bethany Veo, Ian J. Purvis, Maheedhara R. Guda, Kiran K. Velpula
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
SMYD3
medulloblastoma
cyclin D1
cyclin D3
and cell cycle
Online Access:https://www.mdpi.com/2072-6694/14/7/1673

Internet

https://www.mdpi.com/2072-6694/14/7/1673

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