A General Approach to Indoles: Practical Applications for the Synthesis of Highly Functionalized Pharmacophores
The development of a long-term manufacturing route to a potent and selective KDR kinase inhibitor has led to the discovery of several novel methodologies for the general synthesis of indoles. The key transformations involved addition of a trimethylsilylnitro benzene to an aromatic aldehyde...
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
2006-09-01
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| Series: | CHIMIA |
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| Online Access: | https://chimia.ch/chimia/article/view/4205 |