Maximum tolerated dose and toxicity evaluation of orally administered docetaxel granule in mice

Oral delivery of chemotherapy drugs is the most favorable and preferred route of drug administration. However, because of poor solubility and/or permeability, most chemotherapy drugs are given by intravenous administration. Docetaxel (DTX) is a potent chemotherapy drug that inhibits microtubular dep...

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Bibliographic Details
Main Authors: Xiaowei Dong, Jinmin Zhang
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750024000398