Synthetic Ruthenium Complex TQ-6 Potently Recovers Cerebral Ischemic Stroke: Attenuation of Microglia and Platelet Activation

Synthetic Ruthenium Complex TQ-6 Potently Recovers Cerebral Ischemic Stroke: Attenuation of Microglia and Platelet Activation

Activated microglia are crucial in the regulation of neuronal homeostasis and neuroinflammation. They also contribute to neuropathological processes after ischemic stroke. Thus, finding new approaches for reducing neuroinflammation has gained considerable attention. The metal ruthenium has gained no...

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Bibliographic Details
Main Authors: Chih-Hsuan Hsia, Thanasekaran Jayakumar, Joen-Rong Sheu, Chih-Wei Hsia, Wei-Chieh Huang, Marappan Velusamy, Li-Ming Lien
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Journal of Clinical Medicine
Subjects:
BV2 microglia
brain infarct/edema
neuroinflammation
Nrf2/HO-1
NF-κB
platelets
Online Access:https://www.mdpi.com/2077-0383/9/4/996

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https://www.mdpi.com/2077-0383/9/4/996

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