Cellular lethal damage of 64Cu incorporated in mammalian genome evaluated with Monte Carlo methods

Cellular lethal damage of 64Cu incorporated in mammalian genome evaluated with Monte Carlo methods

PurposeTargeted Radionuclide Therapy (TRT) with Auger Emitters (AE) is a technique that allows targeting specific sites on tumor cells using radionuclides. The toxicity of AE is critically dependent on its proximity to the DNA. The aim of this study is to quantify the DNA damage and radiotherapeutic...

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Bibliographic Details
Main Authors: Jhonatan Carrasco-Hernandez, José Ramos-Méndez, Elizabeth Padilla-Rodal, Miguel A. Avila-Rodriguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Medicine
Subjects:
targeted radionuclide therapy
Auger emitters
DNA
TOPAS-nBio
copper-64
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1253746/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1253746/full

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