CD8<sup>+</sup> Cytotoxic-T-Lymphocyte Breadth Could Facilitate Early Immune Detection of Immunodeficiency Virus-Derived Epitopes with Limited Expression Levels

ABSTRACT Cytotoxic-T-lymphocyte (CTL) responses are important to control the replication of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV). Accumulating evidence suggests that the ability of a few immunodominant T-cell populations to detect and kill HIV/SIV-infected cells...

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Bibliographic Details
Main Authors: Tetsuo Tsukamoto, Hiroyuki Yamamoto, Tetsuro Matano
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00381-18