Comprehensive analysis of the prognosis and immune infiltrates for the BET protein family reveals the significance of BRD4 in glioblastoma multiforme

Comprehensive analysis of the prognosis and immune infiltrates for the BET protein family reveals the significance of BRD4 in glioblastoma multiforme

Background: Glioblastoma multiforme (GBM) is the most common and invasive primary central nervous system tumor. The prognosis after surgery, radiation and chemotherapy is very poor. Bromodomain (BRD) proteins have been identified in oncogenic rearrangements, and play a key role in the development of...

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Bibliographic Details
Main Authors: Yintao Ye, Wei Zhong, Junqiang Qian, Jie Zhang, Tingting Xu, Ruyi Han, Jiangeng Han, Chunwei Wang, Lichao Song, Xianwei Zeng, Hong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
glioblastoma multiforme
BET protein family
prognosis
immune checkpoint
immune infiltrates
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1042490/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1042490/full

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