Water extract of sporoderm-broken spores of Ganoderma lucidum elicits dual antitumor effects by inhibiting p-STAT3/PD-L1 and promoting ferroptosis in castration-resistant prostate cancer

Water extract of sporoderm-broken spores of Ganoderma lucidum elicits dual antitumor effects by inhibiting p-STAT3/PD-L1 and promoting ferroptosis in castration-resistant prostate cancer

Prostate cancer (PCa) is one of the most common malignancies among male patients with cancer pathology worldwide. Owing to the inevitable development of irremediable castration-resistant prostate cancer (CRPC) following intervention with androgen deprivation therapy, new therapeutic strategies are i...

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Bibliographic Details
Main Authors: Xumin Zhou, Jiaqi Wang, Yufei Guo, Houhua Lai, Shilong Cheng, Zhongjie Chen, Hua Li, Qiang Li, Xiangming Mao
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Journal of Functional Foods
Subjects:
Sporoderm-Broken Spores of Ganoderma Lucidum
STAT3
Immunity
Ferroptosis
Castration-resistant Prostate Cancer
Antitumor effect
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624000203

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http://www.sciencedirect.com/science/article/pii/S1756464624000203

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