Selective ischemic-hemisphere targeting Ginkgolide B liposomes with improved solubility and therapeutic efficacy for cerebral ischemia-reperfusion injury

Selective ischemic-hemisphere targeting Ginkgolide B liposomes with improved solubility and therapeutic efficacy for cerebral ischemia-reperfusion injury

Cerebral ischemia-reperfusion injury (CI/RI) remains the main cause of disability and death in stroke patients due to lack of effective therapeutic strategies. One of the main issues related to CI/RI treatment is the presence of the blood-brain barrier (BBB), which affects the intracerebral delivery...

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Bibliographic Details
Main Authors: Yang Li, Miaomiao Zhang, Shiyi Li, Longlong Zhang, Jisu Kim, Qiujun Qiu, Weigen Lu, Jianxin Wang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Ginkgolide B
Cerebral ischemia reperfusion injury (CI/RI)
Docosahexaenoic acid
Liposomes
Brain targeting
Microglia
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087623000107

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http://www.sciencedirect.com/science/article/pii/S1818087623000107

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