FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression

FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression

Abstract Background FLI1 is an oncogenic transcription factor that promotes diverse malignancies through mechanisms that are not fully understood. Herein, FLI1 is shown to regulate the expression of Ubiquitin Associated and SH3 Domain Containing A/B (UBASH3A/B) genes. UBASH3B and UBASH3A are found t...

Full description

Bibliographic Details
Main Authors: Jie Wang, Chunlin Wang, Anling Hu, Kunlin Yu, Yi Kuang, Babu Gajendran, Eldad Zacksenhaus, Klarke Michael Sample, Xiao Xiao, Wuling Liu, Yaacov Ben-David
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Cancer
Subjects:
FLI1
Transcriptional regulation
UBASH3A
UBASH3B
HSPA1B
AP1
Online Access:https://doi.org/10.1186/s12885-024-12075-2

Internet

https://doi.org/10.1186/s12885-024-12075-2

Similar Items