Cancer organoid-based diagnosis reactivity prediction (CODRP) index-based anticancer drug sensitivity test in ALK-rearrangement positive non-small cell lung cancer (NSCLC)

Cancer organoid-based diagnosis reactivity prediction (CODRP) index-based anticancer drug sensitivity test in ALK-rearrangement positive non-small cell lung cancer (NSCLC)

Abstract Background Recently, cancer organoid-based drug sensitivity tests have been studied to predict patient responses to anticancer drugs. The area under curve (AUC) or IC50 value of the dose-response curve (DRC) is used to differentiate between sensitive and resistant patient‘s groups. This stu...

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Bibliographic Details
Main Authors: Sang-Yun Lee, Hyeong Jun Cho, Jimin Choi, Bosung Ku, Seok Whan Moon, Mi Hyoung Moon, Kyung Soo Kim, Kwanyong Hyun, Tae-Jung Kim, Yeoun Eun Sung, Yongki Hwang, Eunyoung Lee, Dong Hyuck Ahn, Joon Young Choi, Jeong Uk Lim, Chan Kwon Park, Sung Won Kim, Seung Joon Kim, In-Seong Koo, Woo Seok Jung, Sang-Hyun Lee, Chang Dong Yeo, Dong Woo Lee
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Non-small cell Lung cancer (NSCLC)
High-throughput screening (HTS)
Cancer Organoid-based diagnosis reactivity prediction (CODRP) platform
Patient-derived Organoid (PDO)
3D cell culture
Online Access:https://doi.org/10.1186/s13046-023-02899-4

Internet

https://doi.org/10.1186/s13046-023-02899-4

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