Solving the Evidence Interpretability Crisis in Health Technology Assessment: A Role for Mechanistic Models?

Solving the Evidence Interpretability Crisis in Health Technology Assessment: A Role for Mechanistic Models?

Health technology assessment (HTA) aims to be a systematic, transparent, unbiased synthesis of clinical efficacy, safety, and value of medical products (MPs) to help policymakers, payers, clinicians, and industry to make informed decisions. The evidence available for HTA has gaps—impeding timely pre...

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Bibliographic Details
Main Authors: Eulalie Courcelles, Jean-Pierre Boissel, Jacques Massol, Ingrid Klingmann, Riad Kahoul, Marc Hommel, Emmanuel Pham, Alexander Kulesza
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Medical Technology
Subjects:
modeling and simulation (M&S)
mechanistic evidence
drug development
health technology assessment (HTA)
stakeholder engagement (SE)
mechanistic models
Online Access:https://www.frontiersin.org/articles/10.3389/fmedt.2022.810315/full

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https://www.frontiersin.org/articles/10.3389/fmedt.2022.810315/full

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