Non-apoptotic enteroblast-specific role of the initiator caspase Dronc for development and homeostasis of the Drosophila intestine
Abstract The initiator caspase Dronc is the only CARD-domain containing caspase in Drosophila and is essential for apoptosis. Here, we report that homozygous dronc mutant adult animals are short-lived due to the presence of a poorly developed, defective and leaky intestine. Interestingly, this mutan...
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | English |
| Publicado: |
Nature Portfolio
2021-01-01
|
| Series: | Scientific Reports |
| Acceso en liña: | https://doi.org/10.1038/s41598-021-81261-0 |