Dynamic expression of SNAI2 in prostate cancer predicts tumor progression and drug sensitivity

Dynamic expression of SNAI2 in prostate cancer predicts tumor progression and drug sensitivity

Prostate cancer is a highly heterogeneous disease, understanding the crosstalk between complex genomic and epigenomic alterations will aid in developing targeted therapeutics. We demonstrate that, even though snail family transcriptional repressor 2 (SNAI2) is frequently amplified in prostate cancer...

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Bibliographic Details
Main Authors: Ying Z. Mazzu, YuRou Liao, Subhiksha Nandakumar, Martin Sjöström, Lina E. Jehane, Romina Ghale, Barani Govindarajan, Travis A. Gerke, Gwo‐Shu Mary Lee, Jian‐Hua Luo, Sreenivasa R. Chinni, Lorelei A. Mucci, Felix Y. Feng, Philip W. Kantoff
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Molecular Oncology
Subjects:
dasatinib
DNA methylation
HDAC inhibitor
prostate cancer
SNAI2
TMPRSS2‐ERG
Online Access:https://doi.org/10.1002/1878-0261.13140

Internet

https://doi.org/10.1002/1878-0261.13140

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