Patient-derived organoids: a promising tool for breast cancer research

Patient-derived organoids: a promising tool for breast cancer research

Breast cancer (BC) is the most prevalent malignancy among women worldwide. Traditional research models such as primary cancer cell and patient-derived tumor xenografts (PDTXs) have limitations. Cancer cells lack a tumor microenvironment (TME) and genetic diversity, whereas PDTXs are expensive and ha...

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Bibliographic Details
Main Authors: Yixin Shi, Zhanwen Guan, Gengxi Cai, Yichu Nie, Chuling Zhang, Wei Luo, Jia Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Oncology
Subjects:
breast cancer
patient-derived organoids
tumor microenvironment
drug screening
individualized therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1350935/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1350935/full

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