The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis

The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis

Abstract The choroid plexus (ChP) has been suggested as an alternative central nervous system (CNS) entry site for CCR6+ Th17 cells during the initiation of experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS). To advance our understanding of the importance of...

Full description

Bibliographic Details
Main Authors: Ivana Lazarevic, Sasha Soldati, Josephine A. Mapunda, Henriette Rudolph, Maria Rosito, Alex Cardoso de Oliveira, Gaby Enzmann, Hideaki Nishihara, Hiroshi Ishikawa, Tobias Tenenbaum, Horst Schroten, Britta Engelhardt
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Fluids and Barriers of the CNS
Subjects:
Choroid plexus
Experimental autoimmune encephalomyelitis
CCL20
Th17 cells
T cell trafficking
Online Access:https://doi.org/10.1186/s12987-023-00441-4

Internet

https://doi.org/10.1186/s12987-023-00441-4

Similar Items