SGLT-2 Inhibitors and the Inflammasome: What’s Next in the 21st Century?

The nucleotide-binding domain-like receptor protein 3 (NLRP3) inflammasome in the kidney and the heart is increasingly being suggested to play a key role in mediating inflammation. In the kidney, NLRP3 activation was associated with the progression of diabetic kidney disease. In the heart, activatio...

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Main Authors: Dimitris Kounatidis, Natalia Vallianou, Angelos Evangelopoulos, Ioannis Vlahodimitris, Eugenia Grivakou, Evangelia Kotsi, Krystalia Dimitriou, Alexandros Skourtis, Iordanis Mourouzis
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/15/10/2294