p53 immunostaining pattern is a useful surrogate marker for TP53 gene mutations
Abstract Background TP53 is the most frequently mutated gene in the human cancer, and the awareness of its mutational status is useful in the diagnosis and treatment of cancer patients. In the present study, we investigated the association between TP53 gene mutations and p53 immunohistochemical stai...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | Diagnostic Pathology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13000-022-01273-w |