Inbred SJL mice recapitulate human resistance to Cryptococcus infection due to differential immune activation

Inbred SJL mice recapitulate human resistance to Cryptococcus infection due to differential immune activation

ABSTRACT Cryptococcosis remains a significant threat to human health. While the popular C57BL/6J mouse model of cryptococcosis has some advantages, there are some serious shortcomings that limit the ability of researchers to address the disease. Since humans are resistant to environmental cryptococc...

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Bibliographic Details
Main Authors: M. J. Davis, R. E. Martin, G. M. Pinheiro, E. S. Hoke, S. Moyer, K. Ueno, J. L. Rodriguez-Gil, M. A. Mallett, J. S. Khillan, W. J. Pavan, Y. C. Chang, K. J. Kwon-Chung
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
complement
Cryptococcus neoformans
Th1/Th2
atopic immunity
QTL analysis
Online Access:https://journals.asm.org/doi/10.1128/mbio.02123-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02123-23

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