Pulse pressure and APOE ε4 dose interact to affect cerebral blood flow in older adults without dementia

Pulse pressure and APOE ε4 dose interact to affect cerebral blood flow in older adults without dementia

This study assessed whether the effect of vascular risk on cerebral blood flow (CBF) varies by gene dose of apolipoprotein (APOE) ε4 alleles. 144 older adults without dementia from the Alzheimer's Disease Neuroimaging Initiative underwent arterial spin labeling and T1-weighted MRI, APOE genotyp...

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Bibliographic Details
Main Authors: Lauren Edwards, Kelsey R. Thomas, Alexandra J. Weigand, Emily C. Edmonds, Alexandra L. Clark, Einat K. Brenner, Sarah J. Banks, Paul E. Gilbert, Daniel A. Nation, Lisa Delano-Wood, Mark W. Bondi, Katherine J. Bangen
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cerebral Circulation - Cognition and Behavior
Subjects:
Alzheimer's disease
Apolipoprotein E
Arterial spin labeling
Cerebral blood flow
Pulse pressure
Online Access:http://www.sciencedirect.com/science/article/pii/S2666245024000072

Internet

http://www.sciencedirect.com/science/article/pii/S2666245024000072

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