A single-cell mass cytometry platform to map the effects of preclinical drugs on cartilage homeostasis
No disease-modifying drug exists for osteoarthritis (OA). Despite success in animal models, candidate drugs continue to fail in clinical trials owing to the unmapped interpatient heterogeneity and disease complexity. We used a single-cell platform based on cytometry by time-of-flight (cyTOF) to prec...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Clinical investigation
2022-10-01
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| Series: | JCI Insight |
| Subjects: | |
| Online Access: | https://doi.org/10.1172/jci.insight.160702 |