DNA ligase IV dificiency with elevated serum IgG levels suspected to have myelodysplastic syndrome: a case report

DNA ligase IV dificiency with elevated serum IgG levels suspected to have myelodysplastic syndrome: a case report

Abstract Background Ligase IV (LIG4) dificiency is a very rare clinical syndrome with around 50 cases reported to date. This syndrome is caused by biallelic pathogenic variants in the LIG4 gene, which cause DNA damage repair disorders, mainly manifesting as severe immunodeficiency. Case presentation...

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Bibliographic Details
Main Authors: Miao Huang, Guoqing Dong, Xiyan Lu, Fei Xiao, Qixin Zhou, Shaoyi Zhang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Pediatrics
Subjects:
LIG4 dificiency
Immunodeficiency
Elevated IgG
Case report
Myelodysplastic syndrome
Online Access:https://doi.org/10.1186/s12887-022-03655-x

Internet

https://doi.org/10.1186/s12887-022-03655-x

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