Early-life adversity increases anxiety-like behavior and modifies synaptic protein expression in a region-specific manner

Early-life adversity increases anxiety-like behavior and modifies synaptic protein expression in a region-specific manner

Early-life adversity (ELA) can induce persistent neurological changes and increase the risk for developing affective or substance use disorders. Disruptions to the reward circuitry of the brain and pathways serving motivation and emotion have been implicated in the link between ELA and altered adult...

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Bibliographic Details
Main Authors: Jameel N. Hamdan, Jorge A. Sierra-Fonseca, Rodolfo J. Flores, Sigifredo Saucedo, Manuel Miranda-Arango, Laura E. O’Dell, Kristin L. Gosselink
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
stress
maternal separation
neuroplasticity
methamphetamine
addiction
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2022.1008556/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2022.1008556/full

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