Aquaporin-9 facilitates liver regeneration following hepatectomy

Aquaporin-9 facilitates liver regeneration following hepatectomy

Aquaporin-9 (AQP9) is an aquaglyceroporin strongly expressed in the basolateral membrane of hepatocytes facing the sinusoids. AQP9 is permeable to hydrogen peroxide (H2O2) and glycerol as well as to water. Here, we report impaired liver regeneration in AQP9−/− mice which involves altered steady-stat...

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Bibliographic Details
Main Authors: Bo Zhang, Dongyue Lv, Yang Chen, Weijue Nie, Yang Jiao, Junqi Zhang, Xiaoxiao Zhou, Xiao Wu, Siqing Chen, Tonghui Ma
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Redox Biology
Subjects:
Liver regeneration
Aquaporin-9
Partial hepatectomy
Hydrogen peroxide
Oxidative stress
Gluconeogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722000180

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http://www.sciencedirect.com/science/article/pii/S2213231722000180

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