Implications for Immunotherapy of Breast Cancer by Understanding the Microenvironment of a Solid Tumor

Breast cancer is poorly immunogenic due to immunosuppressive mechanisms produced in part by the tumor microenvironment (TME). The TME is a peritumoral area containing significant quantities of (1) cancer-associated fibroblasts (CAF), (2) tumor-infiltrating lymphocytes (TIL) and (3) tumor-associated...

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Bibliographic Details
Main Authors: Alexander S. Franzén, Martin J. Raftery, Gabriele Pecher
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/13/3178