Design of combination therapy for engineered bacterial therapeutics in non-small cell lung cancer

Abstract Synthetic biology enables the engineering of bacteria to safely deliver potent payloads to tumors for effective anti-cancer therapies. However, a central challenge for translation is determining ideal bacterial therapy candidates for specific cancers and integrating them with other drug tre...

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Bibliographic Details
Main Authors: Dhruba Deb, Yangfan Wu, Courtney Coker, Tetsuhiro Harimoto, Ruoqi Huang, Tal Danino
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-26105-1