Stachydrine ameliorates hypoxia reoxygenation injury of cardiomyocyte via enhancing SIRT1-Nrf2 pathway
Abstract Background Hypoxia/reoxygenation (H/R)-induced cardiomyocyte cell apoptosis is critical in developing myocardial infarction. Stachydrine (STA), an active constituent of Leonurus heterophyllus sweet, could have a protective effect on myocardial H/R injury, which remains unexplored. Therefore...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-09-01
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Series: | Journal of Cardiothoracic Surgery |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13019-023-02363-6 |