Stachydrine ameliorates hypoxia reoxygenation injury of cardiomyocyte via enhancing SIRT1-Nrf2 pathway

Abstract Background Hypoxia/reoxygenation (H/R)-induced cardiomyocyte cell apoptosis is critical in developing myocardial infarction. Stachydrine (STA), an active constituent of Leonurus heterophyllus sweet, could have a protective effect on myocardial H/R injury, which remains unexplored. Therefore...

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Bibliographic Details
Main Authors: Xi Zhu, Yingbiao Wu, Xiaogang Zhang, Wei Gu, Zhongping Ning
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:https://doi.org/10.1186/s13019-023-02363-6