Influence of Hypoxic and Hyperoxic Preconditioning on Endothelial Function in a Model of Myocardial Ischemia-Reperfusion Injury with Cardiopulmonary Bypass (Experimental Study)

Influence of Hypoxic and Hyperoxic Preconditioning on Endothelial Function in a Model of Myocardial Ischemia-Reperfusion Injury with Cardiopulmonary Bypass (Experimental Study)

The aim of the experiment was to evaluate the effect of preconditioning based on changes in inspiratory oxygen fraction on endothelial function in the model of ischemia-reperfusion injury of the myocardium in the condition of cardiopulmonary bypass. The prospective randomized study included 32 rabbi...

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Bibliographic Details
Main Authors: Irina A. Mandel, Yuri K. Podoksenov, Irina V. Suhodolo, Darya A. An, Sergey L. Mikheev, Andrey Yu. Podoksenov, Yulia S. Svirko, Anna M. Gusakova, Vladimir M. Shipulin, Andrey G. Yavorovskiy
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
hypoxic preconditioning
hyperoxic preconditioning
ischemia-reperfusion injury
endothelial dysfunction
nitric oxide
endothelin-1
Online Access:https://www.mdpi.com/1422-0067/21/15/5336

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https://www.mdpi.com/1422-0067/21/15/5336

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