Comparative transcriptomes reveal pro-survival and cytotoxic programs of mucosal-associated invariant T cells upon Bacillus Calmette–Guérin stimulation

Comparative transcriptomes reveal pro-survival and cytotoxic programs of mucosal-associated invariant T cells upon Bacillus Calmette–Guérin stimulation

Mucosal-associated invariant T (MAIT) cells are protective against tuberculous and non-tuberculous mycobacterial infections with poorly understood mechanisms. Despite an innate-like nature, MAIT cell responses remain heterogeneous in bacterial infections. To comprehensively characterize MAIT activat...

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Bibliographic Details
Main Authors: Manju Sharma, Liang Niu, Xiang Zhang, Shouxiong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
transcriptome
MHC-related protein 1 (MR1)
Bacillus Calmette-Guérin (BCG)
mucosal-associated invariant T (MAIT) cells
Mycobacterium tuberculosis (M. tuberculosis)
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1134119/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1134119/full

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