Comparative transcriptomes reveal pro-survival and cytotoxic programs of mucosal-associated invariant T cells upon Bacillus Calmette–Guérin stimulation

Comparative transcriptomes reveal pro-survival and cytotoxic programs of mucosal-associated invariant T cells upon Bacillus Calmette–Guérin stimulation

Mucosal-associated invariant T (MAIT) cells are protective against tuberculous and non-tuberculous mycobacterial infections with poorly understood mechanisms. Despite an innate-like nature, MAIT cell responses remain heterogeneous in bacterial infections. To comprehensively characterize MAIT activat...

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Bibliographic Details
Main Authors:	Manju Sharma, Liang Niu, Xiang Zhang, Shouxiong Huang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Series:	Frontiers in Cellular and Infection Microbiology
Subjects:	transcriptome MHC-related protein 1 (MR1) Bacillus Calmette-Guérin (BCG) mucosal-associated invariant T (MAIT) cells Mycobacterium tuberculosis (M. tuberculosis)
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1134119/full

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