Neurosteroids and their role in sex-specific epilepsies

Neurosteroids and their role in sex-specific epilepsies

Neurosteroids are involved in sex-specific epilepsies. Allopregnanolone and related endogenous neurosteroids in the brain control excessive neuronal excitability and seizure susceptibility. Neurosteroids activate GABA-A receptors, especially extrasynaptic αγδ-GABA-A receptor subtypes that mediate to...

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Bibliographic Details
Main Author: Doodipala Samba Reddy
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Neurobiology of Disease
Subjects:
Allopregnanolone
Neurosteroid
Progesterone
Catamenial epilepsy
GABA-A receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114001740

Internet

http://www.sciencedirect.com/science/article/pii/S0969996114001740

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