Compiler-aided systematic construction of large-scale DNA strand displacement circuits using unpurified components

DNA circuits hold promise for advancing information-based molecular technologies, yet it is challenging to design and construct them in practice. Thubagereet al. build DNA strand displacement circuits using unpurified strands whose sequences are automatically generated from a user-friendly compiler.

Bibliographic Details
Main Authors: Anupama J. Thubagere, Chris Thachuk, Joseph Berleant, Robert F. Johnson, Diana A. Ardelean, Kevin M. Cherry, Lulu Qian
Format: Article
Language:English
Published: Nature Portfolio 2017-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14373