Economic impact of metagenomic next-generation sequencing versus traditional bacterial culture for postoperative central nervous system infections using a decision analysis mode: study protocol for a randomized controlled trial

Economic impact of metagenomic next-generation sequencing versus traditional bacterial culture for postoperative central nervous system infections using a decision analysis mode: study protocol for a randomized controlled trial

ABSTRACT Central nervous system infections (CNSIs) are common complications after neurosurgery with a poor prognosis. The traditional microbiological culture methodology has a low detection rate and time consuming. Metagenomic next-generation sequencing (mNGS) has demonstrated the advantages of bein...

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Bibliographic Details
Main Authors: Ying Tian, Ran Gao, Yumei Wang, Yimin Zhou, Shanshan Xu, Yuqing Duan, Wenyi Lv, Shuya Wang, Mengxue Hou, Yuqing Chen, Fangqiang Li, Wei Gao, Linlin Zhang, Jian-Xin Zhou
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mSystems
Subjects:
central nervous system infections
metagenomic next-generation sequencing
cerebrospinal fluid culture
health economics
diagnosis
Online Access:https://journals.asm.org/doi/10.1128/msystems.00581-23

Internet

https://journals.asm.org/doi/10.1128/msystems.00581-23

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