Function and Regulation of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) / CRISPR Associated (Cas) Systems

Phages are the most abundant biological entities on earth and pose a constant challenge to their bacterial hosts. Thus, bacteria have evolved numerous ‘innate’ mechanisms of defense against phage, such as abortive infection or restriction/modification systems. In contrast, the clustered regularly in...

Full description

Bibliographic Details
Main Authors: Peter C. Fineran, James T. Chang, Corinna Richter
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/4/10/2291