Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels

Rlip76 (Rlip) is a multifunctional membrane protein that facilitates the high metabolic rates of cancer cells through the efflux of toxic metabolites and other functions. Rlip inhibition or depletion results in broad-spectrum anti-cancer effects in vitro and in vivo. Rlip depletion effectively suppr...

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Bibliographic Details
Main Authors: Ashly Hindle, Chhanda Bose, Jihyun Lee, Philip T. Palade, Christopher J. Peterson, P. Hemachandra Reddy, Sanjay Awasthi, Sharda P. Singh
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/3/527