Pan-cancer analysis of SLC2A family genes as prognostic biomarkers and therapeutic targets

Pan-cancer analysis of SLC2A family genes as prognostic biomarkers and therapeutic targets

Background: The major facilitator superfamily glucose transporters (GLUTs), encoded by solute carrier 2A (SLC2A) genes, mediate the transmembrane movement and uptake of glucose. To satisfy the improved energy demands, glycolysis flux is increased in cancers compared with healthy tissues. Multiple di...

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Bibliographic Details
Main Authors: Yating Liu, Xinyu Li, Jie Yang, Shanshan Chen, Changyu Zhu, Yijun Shi, Shoutao Dang, Weitao Zhang, Wei Li
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
SLC2A family genes
Pan-cancer
Prognosis
Tumor microenvironment
Therapeutic targets
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402405686X

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http://www.sciencedirect.com/science/article/pii/S240584402405686X

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