Pan-cancer analysis of SLC2A family genes as prognostic biomarkers and therapeutic targets
Background: The major facilitator superfamily glucose transporters (GLUTs), encoded by solute carrier 2A (SLC2A) genes, mediate the transmembrane movement and uptake of glucose. To satisfy the improved energy demands, glycolysis flux is increased in cancers compared with healthy tissues. Multiple di...
Main Authors: | Yating Liu, Xinyu Li, Jie Yang, Shanshan Chen, Changyu Zhu, Yijun Shi, Shoutao Dang, Weitao Zhang, Wei Li |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-04-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S240584402405686X |
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