Biodistribution and elimination kinetics of systemic Stx2 by the Stx2A and Stx2B subunit-specific human monoclonal antibodies in mice

<p>Abstract</p> <p>Background</p> <p>Hemolytic uremic syndrome (HUS) leading to acute kidney failure, is a condition linked to the production of primarily Shiga toxin 2 (Stx2) by some <it>E. coli</it> serotypes. We have previously shown that Stx2 A subunit-s...

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Bibliographic Details
Main Authors: Sheoran Abhineet, Jeong Kwang-il, Mukherjee Jean, Wiffin Anthony, Singh Pradeep, Tzipori Saul
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Immunology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2172/13/27