Metabolomic analysis of dietary‐restriction‐induced attenuation of sarcopenia in prematurely aging DNA repair‐deficient mice

Metabolomic analysis of dietary‐restriction‐induced attenuation of sarcopenia in prematurely aging DNA repair‐deficient mice

Abstract Background Sarcopenia is characterized by loss of skeletal muscle mass and function, and is a major risk factor for disability and independence in the elderly. Effective medication is not available. Dietary restriction (DR) has been found to attenuate aging and aging‐related diseases, inclu...

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Bibliographic Details
Main Authors: Yupeng He, Wei Yang, Luojiao Huang, Marlien Admiraal‐van Mever, Rawi Ramautar, Amy Harms, Yvonne Rijksen, Renata M.C. Brandt, Sander Barnhoorn, Kimberly Smit, Dick Jaarsma, Peter Lindenburg, Jan H. J. Hoeijmakers, Wilbert P. Vermeij, Thomas Hankemeier
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Dietary restriction
Energy generation
Inflammation
Muscle aging
Oxidative stress
Progeria
Online Access:https://doi.org/10.1002/jcsm.13433

Internet

https://doi.org/10.1002/jcsm.13433

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