Three doses of COVID-19 mRNA vaccine induce class-switched antibody responses in inflammatory arthritis patients on immunomodulatory therapies

Three doses of COVID-19 mRNA vaccine induce class-switched antibody responses in inflammatory arthritis patients on immunomodulatory therapies

Patients with inflammatory arthritis (IA) are at increased risk of severe COVID-19 due to medication-induced immunosuppression that impairs host defenses. The aim of this study was to assess antibody and B cell responses to COVID-19 mRNA vaccination in IA patients receiving immunomodulatory therapie...

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Bibliographic Details
Main Authors: Jenny M. Lee, Alexis Figueroa, Jaiprasath Sachithanandham, Maggie Li, Caoilfhionn M. Connolly, Janna R. Shapiro, Yiqun Chen, Michelle Jones, Venkata Gayatri Dhara, Marilyn Towns, John S. Lee, Stephanie R. Peralta, Aaron M. Milstone, Michael Betenbaugh, Amanda K. Debes, Joel Blankson, Ioannis Sitaras, Steve Yoon, Elizabeth A. Thompson, Clifton O. Bingham, Sabra L. Klein, Andrew Pekosz, Justin R. Bailey
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
mRNA vaccines
immunosuppression
inflammatory arthritis
variants of concern
serological response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1266370/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1266370/full

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