Lipopolysaccharides (LPSs) as Potent Neurotoxic Glycolipids in Alzheimer’s Disease (AD)

Lipopolysaccharides (LPSs) as Potent Neurotoxic Glycolipids in Alzheimer’s Disease (AD)

Lipopolysaccharides (LPSs) are microbiome-derived glycolipids that are among the most potent pro-inflammatory neurotoxins known. In <i>Homo sapiens</i>, the major sources of LPSs are gastrointestinal (GI)-tract-resident facultative anaerobic Gram-negative bacilli, including <i>Bact...

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Bibliographic Details
Main Authors: Yuhai Zhao, Vivian R. Jaber, Aileen I. Pogue, Nathan M. Sharfman, Christopher Taylor, Walter J. Lukiw
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease (AD)
dysbiosis
gastrointestinal tract
lipopolysaccharide (LPS)
microbiome
miRNA-30
Online Access:https://www.mdpi.com/1422-0067/23/20/12671

Internet

https://www.mdpi.com/1422-0067/23/20/12671

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